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For Wegovy specifically, the cardiovascular indication added in March 2024 (based on SELECT trial, Lincoff et al
Chronic cytoprotection: pentadecapeptide BPC 157, ranitidine and propranolol prevent, [PMID: 11595453] Laboratory literature summary: Chronic cytoprotection: pentadecapeptide BPC 157, ranitidine and propranolol prevent, attenuate and reverse the gastric lesions
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(But as the review points out, some research is conflicting.) Exactly whats going on needs further study
Analysis of publicly available datasets for mtRNR1 (MOTS-c) mRNA levels in pancreatic islet cells or EndoC-HB1 cells treated with inflammatory cytokines showed that MOTS-c levels decrease under T1D conditions (Fig
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