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Even at reduced doses, this dual action continues to: In clinical research, patients who transitioned to lower maintenance doses after achieving weight loss showed significantly better long-term results compared to those who stopped completely

However, conflicting findings and gaps in understanding persist, calling for further research into the mechanisms underlying the influence of DPP-4 on bone metabolism

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Weight loss is rarely linear, and factors such as water retention, hormonal fluctuations, muscle gain, and normal metabolic adaptation can temporarily slow progress

However, a link between OC use and increased liver parameters has been proposed [53]