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The primary endpoints was the percent change from baseline in body weight, while secondary endpoints included change from baseline in body mass index (BMI), waist circumference and systolic blood pressure

The process of bile acid transport from hepatocytes into the biliary tract via canalicular transporters is sensitive to disturbances, as evidenced by elevated bilirubin levels that occur upon minor liver injury

Altogether these results suggest that GSTLs are mainly expressed in organs that have a more intense secondary metabolism, which is consistent with the proposal that GSTLs are involved in the biosynthesis and/or maintenance of the flavonoid pool (see the Section Enzymatic Properties and Physiological Roles)