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Ideal timing: Morning on an empty stomach Before breakfast with water At a fixed time daily for consistency If taking multiple doses: Glutathione can be taken once daily Vitamin C may be divided between morning and evening if needed Morning intake is commonly preferred because the body is naturally in a detox-supportive state after waking up

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CL Answer I thought the B vitamins were all water soluble and did not build up in the body, so you would not build up toxic levels