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Lys 16 Replacing the Gly 22 of GLP-1 with Ala or Aib slightly decreased both its affinity and activity (Ala IC 50 : 0.27 nM0.57 nM;EC 50 : 2.6 nM4 nM)
Data are expressed as mean standard deviation (SD) from at least three independent experiments unless otherwise specified in the figure legend
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