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Additionally, cost and insurance access play critical roles in determining which medications patients can obtain consistently
Understanding the broader GLP-1 and fatigue connection helps contextualize why tiredness during treatment can feel so pervasive
Both postmenopausal women on hormone therapy and those not on hormone therapy had improvements in cardiometabolic risk markers
Berberine, for example, has been studied for effects on blood sugar and body weight
Most patients experience constipation during the first 2-4 weeks as the body adjusts to the medication's effect on stomach emptying
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![Cardiovascular disease continuum-GLP-1 action. Adapted from [46]](https://www.researchgate.net/publication/357072789/figure/fig1/AS:1146405179654167@1650335702879/Cardiovascular-disease-continuum-GLP-1-action-Adapted-from-46.png)
