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ISCT 2018, 2018
The NF-B pathway functions as a central pro-survival and pro-inflammatory transcription factor that promotes tumor progression by suppressing tumor suppressors such as phosphatase and tensin homolog (PTEN), thereby indirectly enhancing PI3K/AKT signaling and supporting cancer cell viability
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therefore, increases energy levels because it ensures that fatty acids get transported and are burned inside the mitochondria for energy
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