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When you skip a week and dose every 14 days, blood levels drop significantly between injections, reducing appetite suppression and blood sugar control
However, bupropion is reasonably stable in acidic environments, so the clinical significance may be minimal
Presented for research literature review only Kuka J et al
Synthesis and characterization of new bivalent agents as melatonin- and histamine [PMID: 25222552] Laboratory literature summary: Synthesis and characterization of new bivalent agents as melatonin- and histamine H3-ligands
New England Journal of Medicine, 375( 19), 1834-1844
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