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(2015) Genetic variations in glutathione pathway genes predict cancer recurrence in patients treated with transurethral resection and Bacillus CalmetteGuerin instillation for non-muscle invasive bladder cancer, Ann

yet the digoxin blood concentration remained within therapeutic levels and the AUC did not change [14]

Pregnancy and breastfeeding are clear contraindications - we lack sufficient safety data on high-dose IV administration during these times

Supplementing without lab confirmation can be unnecessary or even harmful (e.g., excess iron can cause GI symptoms or toxicity)

The Protonix (pantoprazole) at-risk launch by Teva and Sun Pharmaceuticals illustrates the catastrophic downside