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NRF2 NRF2 (nuclear factor erythroid 2-related factor 2) is a central transcriptional regulator in oxidative stress responses, playing a significant role in radiation-induced brain injury [31]
The function of SARS-CoV-2 spike protein is impaired by disulfide-bond disruption with mutation at cysteine-488 and by thiol-reactive N-acetyl-cysteine and glutathione
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MicroRNA miR-212-5p, found at low levels in extracellular vesicles from injured brain tissues in TBI mice, has been identified as a negative regulator of PTGS2a key mediator of ferroptotic signalingsuggesting that miR-212-5p may confer neuroprotection by suppressing ferroptosis (227)
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