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The results of several large randomized controlled trials indicated that maintaining blood glucose at near normal concentrations was the most important step in limiting the risk of diabetic neuropathy and lower extremity amputation (70-72)

Supermarkets, hypermarkets, specialty shops, pharmacies, and other establishments make up the offline distribution channel

These medications work through several mechanisms, including slowing gastric emptying (though this effect may attenuate over time), acting on appetite centers in the hypothalamus, and enhancing feelings of fullness

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