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Another anti-inflammatory medication, anakinra (Kineret), blocks the inflammatory cytokine interleukin-1 (IL-1)
Further, targeted metabolomics and isotope tracing experiments uncovered GGCT as a metabolic orchestrator to prioritize Gln to GSH flux for antioxidant defense, while activating glucose (Glc)-fueled anaplerosis to replenish TCA intermediates to fuel proliferation
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By reducing oxidative stress and neutralizing free radicals, glutathione creates a healthier environment for collagen synthesis
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