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Oral semaglutide (Rybelsus) represents another option, though gastrointestinal side effects remain prevalent with this formulation

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The American Association of Clinical Endocrinologists/American College of Endocrinology consensus statement also recommends either a GLP-1RA or SGLT2i as a preferred treatment option (either as first-line or, more typically, second-line treatment after metformin) over alternative options such as a dipeptidyl peptidase-4 inhibitor, a thiazolidinedione (TZD), or a sulfonylurea (SU), for patients with T2D and ASCVD, stage 3 CKD, or heart failure with reduced ejection fraction [2]

Wegovy and Ozempic cost around $1,000 for a monthly supply

reduce inflammation