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This strategy not only effectively eradicates orthotopic and distal tumors but also enhances the bodys antitumor immune response, offering a promising new approach for CRC therapy

Annexin V binds phosphatidylserines that translocate to the outer leaflet of the membrane during early apoptosis 61 , whereas 7-AAD is a membrane-impermeable DNA dye that labels cells with compromised membrane integrity, identifying cells undergoing lytic forms of cell death such as necrosis, secondary necrosis and pyroptosis 62,63

Small, frequent meals may be better tolerated than larger portions given the delayed gastric emptying induced by GLP-1 medications

Starting at a lower dose and titrating gradually may help reduce discomfort

Some patients may also check whether HSA or FSA funds can be used for eligible expenses