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If you or your weight management doctor raise concerns about side effects, ask about ways to minimize them, such as starting with a lower dose or adjusting your diet

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FE = fixed effects

It is caused when collagen and elastin fibres become damaged after the skin has been stretched for an extended period

GLP-1 receptors are present in regions of the brainstem that regulate appetite and the sensation of nausea, including the area postrema, a region sometimes called the vomiting center that sits outside the blood brain barrier and samples the bloodstream directly, and activity there contributes to reduced hunger and, at higher signaling levels, to nausea