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Safety, Unknowns, and PCOS-Specific Cautions Even where retatrutides efficacy signals are strong, its safety in a PCOS population carries specific unknowns that deserve emphasis precisely because the target group is young women, many of whom may become pregnant
The medication acts on the beta cells of the pancreas to promote insulin release, which lowers blood sugar levels
The standard escalation path reaches 1.0 mg (often considered minimally effective) by week 16, progressing through 0.25 mg, 0.5 mg, 0.75 mg increments
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