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The above experiments indicate that certain critical substances from A

2 Preparation of GSH standard solutions

Moreover, it reduces free radical production by suppressing cytochrome P450 enzyme activity.16 Growing evidence indicates that melatonin exerts significant protective effects on reproductive tissues through its potent antioxidant and anti-apoptotic properties.17-19 Experimental studies in both female and male models have shown that melatonin reduces oxidative stress markers, preserves follicular and testicular structure, and ameliorates apoptosis-related damage.18 In this study, the potential protective effects of Mel and GSH were investigated against CARB-induced ovarian damage in rats