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In major semaglutide trials (SUSTAIN series), depression or depressed mood was reported in less than 2% of participants, similar to placebo groups
Study: Glucagon-like peptide-1 receptor agonists and muscle mass effects
Mechanistically, GHRP-6 sustained cellular antioxidant defense, upregulated the prosurvival gene Bcl-2, and preserved cardiomyocyte mitochondrial integrity
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regulates cellular redox state through the GSH:GSSG couple
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