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For example, IL-4 receptor alpha (IL-4R), which binds to both IL-4 and IL-13, has been found on excitatory and inhibitory neurons of the hippocampus, and signaling along this axis is necessary for proper excitatory and inhibitory potentials in both humans and mice [115]

IGF-1 is thought to pull glucose out of the bloodstream and boost the effects of insulin (24, 25)

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Genetic variants in growth factor receptors and collagen regulation pathways may influence tissue remodeling capacity