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At 10 mg weekly, that same vial lasts only 5 weeks
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This supports the hypothesis that rapid weight reduction rather than the medication itself is the primary causative factor
In hemodialysis patients, due to reduced renal clearance, carnitine depletion and acylcarnitine accumulation become significant, resulting in an abnormal increase in the ratio of acylcarnitine to free carnitine in plasma, which in turn inhibits cardiac fatty acid metabolism [261]
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