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The identified literature was narratively synthesized without formal study selection protocols, risk-of-bias assessment, or quantitative meta-analysis
A separate 2025 trial in NEJM Evidence (Shah et al.) in adults with T1D and obesity on AID found that around one in three semaglutide-treated participants met a combined goal of improved time in range, low hypoglycemia, and at least 5% weight loss
Case Study: Tackling the Liver Disease Challenge: NAFLD and NASH, currently without approved treatments, affect millions
10.1081/JAS-200038447
The safety profile of tesofensine was favorable, and reductions in obesity-related risk factors were observed
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