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According to clinicians such as Jarred Mait, MD, the focus is not on pairing peptides by default, but on determining whether each compound aligns with an individual patients goals, injury profile, and overall health status
The Pernicious Anaemia Society notes this is well recognised but not fully understood
The strongest human clinical evidence is for topical use, including the Leyden 2002 photoaging trial and a 2023 NEEL gel topical study reporting an average 28% increase in skin collagen density at 3 months
These two research directions overlap in the literature but represent distinct lines of inquiry, each rooted in a different aspect of the peptides mechanism
It is always best to consult with your doctor before starting any new supplement during this time
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