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Importantly, these changes were observed without significant reductions in food consumption, pointing to enhanced energy metabolism rather than appetite suppression as the primary mechanism
Remember that clinical trials failed to demonstrate statistically significant weight loss in the largest study, leading to development termination in 2007
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Additionally, early clinical data suggests Tesofensine may help preserve lean muscle mass during caloric restriction a key differentiator for athletes and bodybuilders compared to other weight loss drugs
Total cholesterol levels fell by approximately 30%
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