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In laboratory settings, AOD-9604 has been studied for its interactions with beta-3 adrenergic receptors, which play a role in adipocyte metabolism

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This enzyme is expressed on bronchial epithelial cells, endothelial cells, fibroblasts, type II pneumocytes, and infiltrating inflammatory cells (93)

The excess production of these ROS is controlled and co-ordinated by various endogenous antioxidant defense mechanisms which come into existence in the presence of exogenous irritants