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Liraglutide has more years of post-market safety data (since 2010), but tirzepatide clinical trials involved large patient populations with rigorous safety monitoring
The most common side effects for all three are gastrointestinal issues, including: Nausea Vomiting Diarrhea Constipation Other possible side effects include: Indigestion Bloating Fatigue Injection site reactions Hypoglycemia, or low blood sugar, is a serious side effect of all three drugs and warrants urgent medical attention
Indeed, we see increased UCK2 expression 72 h post 5FU treatment (Fig
For researchers concerned about fatigue during GLP-1 therapy , liver function is worth considering
In one large clinical trial, patients on 2.4 mg of Wegovy each week who received individualized lifestyle counseling sessions, followed a low-calorie diet, and increased physical activity lost an average of almost 15% of their body weight after 68 weeks
