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5C) is a GLP-1 receptor agonist that is based on the structure of exendin-4
Lower susceptibility of female mice to acetaminophen hepatotoxicity: role of mitochondrial glutathione, oxidant stress and c-jun N-terminal kinase
The improvement in nitric oxide signaling contributes significantly to suppression of inflammation and improvement of insulin signaling and vascular function, thereby inhibiting the development of atherosclerotic vascular disease [141]
Importantly, exenatide was much more durable in circulation: it has ~2.4 hours half-life in humans vs just minutes for GLP-1 ( [93] ) ( [94] )
10.1161/JAHA.120.020301 6 BanK.Noyan-AshrafM
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