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Clinical studies show that while GLP-1 peptides like semaglutide and tirzepatide primarily reduce fat mass, some lean muscle is lost as well

Any suspected side effects from these or any other medicines or research chemicals should be reported to the MHRA via the Yellow Card Scheme at yellowcard.mhra.gov.uk

Last reviewed: November 16, 2025 Routine administration of all age-appropriate doses of vaccines at the same visit, also known as coadministration, is acceptable for children, adolescents, and adults if there are no contraindications at the time of the healthcare visit

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