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The hemoglobin concentration served as normalization factor and was measured immediately after sampling in EDTA whole blood using the automated analyzer Celltac- (MEK 6450, Nihon Kohden, Qinlab Diagnostik, Weichs, Germany)

Nausea, vomiting, and other gastrointestinal symptoms are common, particularly when starting or increasing the dose and in T1D trials, these rates were similar to those seen in T2D and obesity trials

Perez-Cerezales S, Boryshpolets S, Afanzar O, Brandis A, Nevo R, Kiss V, Eisenbach M (2015) Involvement of opsins in mammalian sperm thermotaxis