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[20] [21] Seek urgent medical advice if you are already taking a GLP-1 medication and experience: Severe, persistent abdominal pain (possible pancreatitis) A new lump in your neck or changes in your voice Symptoms of severe hypoglycaemia (if taking other diabetes medications) Signs of thyroid dysfunction despite stable levothyroxine therapy Persistent vomiting leading to dehydration or inability to take oral medications Severe right upper abdominal pain, fever or jaundice (possible gallbladder disease) Open communication with your healthcare team ensures that treatment decisions are individualised, evidence-based, and aligned with your health priorities

GLP-1 quiets that down

Major cardiovascular outcome trials include: LEADER trial (liraglutide): Demonstrated a significant reduction in major adverse cardiovascular events (MACE) in patients with type 2 diabetes and high cardiovascular risk SUSTAIN-6 (semaglutide): Showed reduced cardiovascular death, non-fatal myocardial infarction, and non-fatal stroke REWIND (dulaglutide): Confirmed cardiovascular benefits across a broad patient population SELECT trial (semaglutide): Showed reduced MACE in people with obesity without diabetes, though this evidence is not yet fully incorporated into UK labelling [17] These trials consistently found that the modest heart rate increases observed did not translate into adverse cardiovascular outcomes

Chemical peels can be performed year-round, but treatment plans may vary depending on sun exposure and lifestyle

A compounded GLP-1 refers to a medication that has been custom-made by a licensed pharmacy rather than manufactured by a pharmaceutical company