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This is a fancy way of saying lack of blood flow (ie, ischemia) of the front part (ie, anterior) of the optic nerve
Based on the sequence requirements in penetratin for transduction, such as hydrophobicity, amphipathicity, basicity, and the chain length (Khafagy et al., 2010a), a modified peptide designated as shuffle (R,K fix) 2 (RWFKIQMQIRRWKNKK) that exhibits safe and enhanced insulin delivery was developed (Khafagy et al., 2010a)
The answer is pretty straightforward
It is safe and effective
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