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however, HCVHIV co-infection increases oxidative stress more potently than HIV mono-infection 124,125
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The STEP clinical trials the largest studies ever conducted on semaglutide, found that nausea typically resolves within the first two weeks, diarrhea clears within days, and even constipation, the most persistent GI side effect, averages around 47 days before it improves
Patients with certain genetic profiles may experience nausea more quickly or intensely, while others tolerate the medication with minimal digestive discomfort
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