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The Columbia-Suicide Severity Rating Scale was administered to assess suicidal ideation and behavior

DES(1-3) IGF-1 is a truncated variant missing the first three N-terminal amino acids (Gly-Pro-Glu), which also reduces IGFBP binding but through a different structural mechanism removal of the N-terminal tripeptide rather than charge substitution

Topical application of capsaicin, honey-based chamomilla tinc and steroid gargle could reduce BMS symptom temporarily [101, 102]

Given the above literature, it is surprising that a recent proposal suggests certain enteroendocrine cells, including GLP-1 cells, communicate with vagal afferents through synaptic-like transmission 38,39

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