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We also tested the influence of the dimeric macrocycles to cellular responses on murine and canine cell lines (Supplementary Table 5 and Supplementary Fig

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This is achieved by expanding the internal diameter of the needle while maintaining the same external dimensions as a standard thin-walled needle, ensuring compliance with the ISO 9626:2026 requirements for the manufacture of hypodermic needles and medical devices

Benefits Disrupts the survival network of senescent cells: Senescent cells enter a state of permanent growth arrest but resist apoptosis despite accumulating DNA damage and oxidative stress