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CPT1C is involved in cellular energy-sensing pathways and has an important role in the hypothalamic regulation of energy homeostasis 44
I personally have two copies of the MTHFR mutation and am alive and well (with some interventions), while others I have seen have just one copy of a mutated gene, and a lot of symptoms
Fat metabolism by facilitating fatty acid transport into mitochondria in muscle fibers
TREM2 deficiency in TDP-43 mouse model leads to a marked reduction in rod-shaped microglia, accompanied by increased neuronal activity (Xie et al., 2025)
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