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The dose-response relationship proved remarkably linear

Not catastrophically, but measurably

For Jardiance-related issues , maintain good genital hygiene to reduce infection risk, stay well-hydrated (aim for 6-8 glasses of water daily unless on fluid restriction), and monitor for signs of urinary tract infections such as burning during urination, increased frequency, or cloudy urine

The combination of GLP-1RAs and metformin appears to be superior to any single agent in reducing body weight, hyperandrogenaemia, IR, and ovulation disorders in women with PCOS and may even improve metabolic outcomes in women who previously had an inadequate response to metformin [162, 217]

Example: a 5 mg (5,000 mcg) vial reconstituted with 2 mL yields 2,500 mcg/mL