Individuals with type 1 diabetes, thyroid cancer, multiple endocrine neoplasia, or end stage kidney disease at any time until cohort entry or individuals with dialysis or the latest eGFR 70 years, by males versus females, by insulin use, by atherosclerotic cardiovascular disease (i.e., myocardial infraction, angina, coronary artery disease, coronary revascularization, peripheral artery disease, aortic atherosclerotic disease, or cerebrovascular disease), by renal insufficiency (i.e., chronic kidney disease or the latest eGFR 70 years (HR [95% CI]: 0.95 [0.831.08])
Transient mild increases in certain liver enzymes were reported in some participants but generally returned to baseline
This extensive influence on both homeostatic and hedonic dimensions of eating behaviour explains the enduring nature of weight reduction
10.1073/pnas.84.10.3434 Proc
N.Garca-MerinoC.Fernndez-GonzlezR.PericuestaE