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This occurs through the activation of adenylyl cyclase, leading to increased intracellular levels of cyclic AMP (cAMP)
Polyphyllin I induced ferroptosis to suppress the progression of hepatocellular carcinoma through activation of the mitochondrial dysfunction via Nrf2/HO-1/GPX4 axis
Nat Rev Endocrinol (2021) 17(8):48495
On the other hand, following ovulation, the increased activity of Cu/Zn-SOD during the early and mid-luteal phase supports corpus luteum function while its diminished activity during the regression phase is associated with luteolysis and cessation of corpus luteum function, ushering menstruation (127)
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