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E.MuranteT.MuranteD.KoselnyK.LiuY.KimD.et al
Awasthi et al., 2005
B.BrownellK
Owing to hypermethylation of the promoter, RIPK3 is silenced in primary tumours but significantly upregulated in recurrent lesions, with an enhanced dependence on cysteine metabolism, suggesting that targeting RIPK3 may inhibit tumour recurrence [56]
Importantly, these data did not originate from randomized colorectal cancer prevention trials
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