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Many patients use microdosing as a bridge to standard dosing once tolerability is established
3.2 Effect of liraglutide on food and water intake, body composition and glycaemia In addition to its insulinotropic action, GLP-1 has also been shown to reduce food intake and slow gastric emptying ( Figure 2A ), attributable to the low circulating levels of leptin ( Figure 2B ), which is consistent with polydipsia, a recognised feature of diabetes ( Figure 2C )
O'Brien ML, Tew KD
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