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Mechanistic Comparison# Dosing Comparison# Amycretin Dosing# Amycretin dosing is investigational: Subcutaneous: Once-weekly injection, doses up to 60 mg studied in phase 1b/2a over 36 weeks Oral: Daily tablet, doses up to 50 mg (or 2 x 50 mg) studied in phase 1 Phase 2 T2D: Both subcutaneous and oral formulations studied over 36 weeks Phase 3 dose selection will be informed by the completed phase 2 data
Common conversion approximations: semaglutide 0.25mg roughly corresponds to tirzepatide 2.5mg
This form of glutathione has been studied and seems to be quite effective for spot treatments, particularly melasma
Top row: fundus photos from initial presentation
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