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Because the medication works by delaying gastric emptying, it can exacerbate the symptoms of stomach paralysis, leading to severe complications like extreme vomiting, malnutrition, or bowel obstructions
These side effects include diarrhea, fatigue, anxiety, constipation, fast pulse, tingling lips, dry mouth, increased hunger, incontinence, rashes, insomnia, irritability, lightheadedness and nausea
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doi:10.1039/C0SM01218A
Metabolic reprogramming, where M1 polarization relies on glycolysis and the pentose phosphate pathway while M2 polarization favors oxidative phosphorylation and fatty acid oxidation, not only supplies energy but also generates regulatory metabolites
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