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Randomized clinical trials have not confirmed a direct causal link, and most were not designed or powered to detect such rare events

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However, long-term data remains limited

The prescribing structure is clean and the clinicians are publicly listed

This explains the ecosystem that when their blood when they do better by way of their blood sugar, better messaging for insulin, better messaging for glucagon receptor sites also in the arteries and on the heart muscle that were seeing cardiometabolic benefit