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A., Herrera-Estrella, L., Rocha-Sosa, M
Frias JP, Bastyr EJ 3rd, Vignati L, et al
J Neurochem 92(4):798806 Ambery P, Parker VE, Stumvoll M, Posch MG, Heise T, Plum-Moerschel L et al (2018) MEDI0382, a GLP-1 and glucagon receptor dual agonist, in obese or overweight patients with type 2 diabetes: a randomised, controlled, double-blind, ascending dose and phase 2a study
Upon binding, IGF-1R undergoes autophosphorylation, recruiting insulin receptor substrate (IRS) proteins and Shc adaptor molecules
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