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Proteomic analyses have revealed that, although many of the same mouse liver proteins are modified covalently by metabolites of the two compounds in vivo, that acetaminophen selectively forms adducts with various mitochondrial proteins (Myers et al
In addition, studies have shown that the 30- and 90-day mortality of the patients with AKI in ICU was much higher than that of the patients without AKI (Santos et al., 2019)
Clinical Trial Registration: identifier: NCT01366859
Eur J Pharmacol 768:112
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