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El proceso de sntesis comienza con el gen del proglucagn, que se expresa tanto en las clulas L intestinales como en las clulas alfa pancreticas y en ciertas neuronas del sistema nervioso central

The drug, semaglutide, is a weekly shot sold under the brand names Ozempic and Wegovy

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Liraglutide (Saxenda) Liraglutide works through the same GLP-1 pathway but has a different dosing schedule than other options on the market, requiring a daily rather than weekly injection

DOSING USED IN PHASE 3 STUDIES In the most recent studies from the TRIUMPH programme (Phase 3) , retatrutide was administered as follows: Route: Subcutaneous Frequency: Once weekly Study duration: Approximately 68 weeks Phase 3 Schedule Recommended Dosage (Clinical Research Escalation Model) Retatrutide is administered once weekly using a gradual dose escalation to improve tolerability