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Current evidence suggests semaglutide works best as a long-term or indefinite medication for most people
Timing: When to make the switch Clinical guidelines for switching between GLP-1 receptor agonists are as follows: If the discontinued drug (compounded semaglutide) was taken once weekly, the first dose of the second drug (Ozempic) can be administered seven days after discontinuation
The article on how long compounded semaglutide lasts in the fridge discusses stability timelines in detail, and the question of does compounded semaglutide need to be refrigerated has a definitive answer: yes, always
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