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Tesamorelin has also been linked to glucose intolerance and a higher risk of type 2 diabetes, and is contraindicated in pregnancy
Oral GLP-1 biologics (e.g., in early development at Biora and Viking) or small molecule GLP-1R agonists (e.g., Structure Therapeutics), will further improve patient adherence and facilitate clinical uptake of these medications
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While they share many similarities, each has its own unique features
doi: 10.1073/pnas.1216100110CrossRefGoogle ScholarPubMed Nie, L., Liang, J., Shan, F., Xu, Y., Yan, C., Zhou, X., Xia, Q
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