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Acetyl-L-carnitine worked better than the medication at reducing pain during intercourse and minimizing the curve of the penis

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Zabawski Jr EJ, Washak RV, Cohen JB, Cockerell CJ, Brown SM

The various genomic changes causing PWS all lead to loss of expression of the paternally expressed genes on chromosome 15q11.2q13 through loss or failure of expression because the maternal contribution has been programmed by epigenetic factors (eg, DNA methylation) to be silenced