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The retatrutide peptide dosage chart shows that GI side effects nearly doubled in Phase 2 trials when participants were assigned directly to higher doses without titration
Long-term strategy: Weight regain after stopping GLP-1s is well-documented
The Morton 2018 meta-analysis identified 1.6 g/kg as the plateau for muscle gain in resistance-trained adults [9], and the Helms 2014 evidence-based guidance for adults in a calorie deficit recommends 2.3 to 3.1 g per kg of fat-free mass [10] that is per kg of FFM, not total bodyweight, so for a leaner athlete it lands above the 2.0 g/kg total-BW number
If it persists beyond 6 weeks, discuss with your PlexusDx provider about potential zinc or electrolyte factors requiring monitoring
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