There is a striking and concerning lack of human evidence
These routine laboratory tests are not designed to detect the medication itself
Your provider may need to hold the dose escalation, reduce back to the prior tolerated dose, or investigate alternative causes
Incretin mimetics have demonstrated safety and efficacy in advanced kidney disease, however multiple studies have shown that use of GLP1-RA have shown improvements in glycemic control, body weight reductions, improved beta cell function, and decreased incidence hypoglycemia as compared to DPP4i in a general diabetes population 26,27,28,29,30,31 , effects which might explain the reduction of acute healthcare utilization observed in this study of patients with CKD treated with GLP1-RA as compared to DPP4i
*Skeletal Muscle*, 1(1):4